• Age-specific atrial fibrillation incidence, attributable risk factors and risk of stroke and mortality: results from the MORGAM Consortium 

      Morseth, Bente; Geelhoed, Bastiaan; Linneberg, Allan; Johansson, Lars; Kuulasmaa, Kari; Salomaa, Veikko; Iacoviello, Licia; Constanzo, Simona; Söderberg, Stefan; Niiranen, Teemu; Vishram, Julie K.K.; Njølstad, Inger; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Zeller, Tanja; Blankenberg, Stefan; Ojeda, Francisco; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      <p><i>Background:</i> The main aim was to examine age-specific risk factor associations with incident atrial fibrillation (AF) and their attributable fraction in a large European cohort. Additionally, we aimed to examine risk of stroke and mortality in relation to new-onset AF across age. <p><i>Methods:</i> We used individual-level data (n=66 951, 49.1% men, age range 40–98 years at baseline) from ...
    • Risk Factors, Subsequent Disease Onset, and Prognostic Impact of Myocardial Infarction and Atrial Fibrillation 

      Camen, Stephan; Csengeri, Dora; Geelhoed, Bastiaan; Niiranen, Teemu; Gianfagna, Francesco; Vishram-Nielsen, Julie K.; Costanzo, Simona; Söderberg, Stefan; Vartiainen, Erkki; Börschel, Christin S.; Donati, Maria Benedetta; Løchen, Maja-Lisa; Ojeda, Francisco M.; Kontto, Jukka; Mathiesen, Ellisiv B.; Jensen, Steen; Koenig, Wolfgang; Kee, Frank; de Gaetano, Giovanni; Zeller, Tanja; Jørgensen, Torben; Tunstall-Pedoe, Hugh; Blankenberg, Stefan; Kuulasmaa, Kari; Linneberg, Allan; Salomaa, Veikko; Iacoviello, Licia; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-24)
      BACKGROUND: Although myocardial infarction (MI) and atrial fibrillation (AF) are frequent comorbidities and share common cardiovascular risk factors, the direction and strength of the association of the risk factors with disease onset, subsequent disease incidence, and mortality are not completely understood.<p> <p>METHODS AND RESULTS: In pooled multivariable Cox regression analyses, we examined ...
    • Risk prediction of atrial fibrillation and its complications in the community using hs troponin I 

      Börschel, Christin S.; Geelhoed, Bastiaan; Niiranen, Teemu; Camen, Stephan; Donati, Maria Benedetta; Havulinna, Aki S.; Gianfagna, Francesco; Palosaari, Tarja; Jousilahti, Pekka; Kontto, Jukka; Vartiainen, Erkki; Ojeda, Francisco M.; den Ruijter, Hester M.; Costanzo, Simona; de Gaetano, Giovanni; Di Castelnuovo, Augusto; Linneberg, Allan; Vishram-Nielsen, Julie K.; Løchen, Maja-Lisa; Koenig, Wolfgang; Jørgensen, Torben; Kuulasmaa, Kari; Blankenberg, Stefan; Iacoviello, Licia; Zeller, Tanja; Söderberg, Stefan; Salomaa, Veikko; Schnabel, Renate B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-05)
      Aims - Atrial fibrillation (AF) is becoming increasingly common. Traditional cardiovascular risk factors (CVRF) do not explain all AF cases. Blood-based biomarkers reflecting cardiac injury such as high-sensitivity troponin I (hsTnI) may help close this gap.<p> <p>Methods - We investigated the predictive ability of hsTnI for incident AF in 45,298 participants (median age 51.4 years, 45.0% men) ...
    • Vertebral fractures assessed by dual-energy X-ray absorptiometry and all-cause mortality. The Tromsø Study 2007-2020 

      Johansson, Jonas; Emaus, Nina; Geelhoed, Bastiaan; Sagelv, Edvard Hamnvik; Morseth, Bente (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-16)
      Vertebral fractures have been associated with increased mortality, but findings are inconclusive, and many vertebral fractures avoid clinical attention. We investigated this association in a general population of 2,476 older adults aged ≥55 years from Tromsø, Norway, who were followed over 2007–2020, using dual-energy x-ray absorptiometry (DXA) at baseline to evaluate vertebral fractures (mild, ...